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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCK
All Species:
17.58
Human Site:
S75
Identified Species:
42.96
UniProt:
P06239
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06239
NP_001036236.1
509
58001
S75
A
L
H
S
Y
E
P
S
H
D
G
D
L
G
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087049
602
68092
I167
A
L
Y
P
Y
D
G
I
H
P
D
D
L
S
F
Dog
Lupus familis
XP_851972
509
58073
S75
A
L
H
S
Y
E
P
S
H
D
G
D
L
G
F
Cat
Felis silvestris
Mouse
Mus musculus
P06240
509
57924
S75
A
L
H
S
Y
E
P
S
H
D
G
D
L
G
F
Rat
Rattus norvegicus
Q01621
509
57871
S75
A
L
H
S
Y
E
P
S
H
D
G
D
L
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514812
514
58948
I79
A
L
Y
P
Y
D
G
I
H
Q
D
D
L
S
F
Chicken
Gallus gallus
P42683
508
58121
T74
A
L
Y
D
Y
E
P
T
H
D
G
D
L
G
L
Frog
Xenopus laevis
P13406
537
60828
R96
A
L
Y
D
Y
E
A
R
T
E
D
D
L
S
F
Zebra Danio
Brachydanio rerio
NP_001035418
503
57487
L72
D
P
A
H
S
D
D
L
G
F
E
K
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
R77
A
L
Y
D
Y
D
A
R
T
D
E
D
L
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
55.8
97.4
N.A.
96.8
96.6
N.A.
63
82.1
54.5
69.7
N.A.
50
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
68.5
98.6
N.A.
98.2
98
N.A.
78.7
91.9
69.8
82.7
N.A.
67.1
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
46.6
100
N.A.
100
100
N.A.
46.6
73.3
46.6
0
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
60
100
N.A.
100
100
N.A.
60
86.6
60
6.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
90
0
10
0
0
0
20
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
30
0
40
10
0
0
60
30
90
0
0
0
% D
% Glu:
0
0
0
0
0
60
0
0
0
10
20
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
80
% F
% Gly:
0
0
0
0
0
0
20
0
10
0
50
0
10
50
0
% G
% His:
0
0
40
10
0
0
0
0
70
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
90
0
0
0
0
0
10
0
0
0
0
90
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
20
0
0
50
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
40
10
0
0
40
0
0
0
0
0
40
0
% S
% Thr:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
90
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _